(3aR,6S,7aR)-7a-Chloro-2-[(4-nitro­phen­yl)sulfon­yl]-1,2,3,6,7,7a-hexa­hydro-3a,6-ep­oxy­iso­indole

نویسندگان

  • Ersin Temel
  • Aydın Demircan
  • Muhammet Kasım Kandemir
  • Medine Çolak
  • Orhan Büyükgüngör
چکیده

In the title compound, C14H13ClN2O5S, the chlorine-substituted tetrahydrofuran ring adopts a twist conformation and the other tetra-hydro-furan ring an envelope conformation with the O atom as the flap. The pyrrolidine ring adopts a twist conformation. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules into zigzag chains running along the b-axis direction.

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منابع مشابه

(3aR,6S,7aR)-7a-Chloro-6-methyl-2-(4-nitro­phenyl­sulfon­yl)-1,2,3,6,7,7a-hexa­hydro-3a,6-ep­oxy­iso­indole

In the title compound, C15H15ClN2O5S, the tetra-hydro-furan ring adopts an envelope conformation with the O atom as the flap. The pyrrolidine ring adopts an envelope conformation with the chlorine-substituted C atom as the flap. In the crystal, two types of C-H⋯O hydrogen bonds generate R (2) 2(20) and R (4) 4(26) rings, with adjacent rings running parallel to ac plane. Further C-H⋯O hydrogen b...

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(3aR,6S,7aR)-7a-Bromo-2-[(4-methyl­phen­yl)sulfon­yl]-1,2,3,6,7,7a-hexa­hydro-3a,6-ep­oxy­isoindole

In the title compound, C(15)H(16)BrNO(3)S, the boat form of the six-membered ring is almost symmetrical with respect to the ep-oxy bridge. The two five-membered rings generated by the ep-oxy bridge of the six-membered ring adopt envelope conformations, whereas the N-containing five-membered ring adopts a twisted conformation. In the crystal, mol-ecules are linked by C-H⋯O hydrogen bonds.

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(3aR,6S,7aR)-7a-Bromo-2-methyl­sulfonyl-1,2,3,6,7,7a-hexa­hydro-3a,6-ep­oxy­isoindole

In the title compound, C(9)H(12)BrNO(3)S, the two tetra-hydro-furan rings adopt envelope conformations, the pyrrolidine ring adopts a half-chair conformation and the six-membered ring is in a boat conformation. In the crystal, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into R(2) (2)(8) and R(2) (2)(14) rings along the b-axis direction.

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(3aR*,6S*,7aR*)-7a-Chloro-6-methyl-2-(4-methyl­phenyl­sulfon­yl)-2,3,3a,6,7,7a-hexa­hydro-3a,6-ep­oxy-1H-isoindole

In the title compound, C(16)H(18)ClNO(3)S, the six-membered ring has a boat conformation. The two five-membered rings with the bridging O atom adopt envelope conformations, whereas the N-containing five-membered ring adopts a twisted conformation. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional network.

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(3aR*,6S*,7S*,7aR*)-2-(4-Methoxy­benz­yl)-7-(4-nitro­phen­yl)-6-phenyl-3a,6,7,7a-tetra­hydro­isoindolin-1-one

The title compound, C(28)H(26)N(2)O(4), crystallizes as a racemate with four stereogenic centers. In the molecule, the pyrrolidone ring adopts an envelope conformation and the cyclo-hexene ring has a twisted envelope conformation. In the crystal structure, mol-ecules are linked by weak inter-molecular C-H⋯O hydrogen bonds.

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عنوان ژورنال:

دوره 69  شماره 

صفحات  -

تاریخ انتشار 2013